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Blockade of complement activation pathways abrogates serum sensitivity of VSV-GP. Serum sensitivity assays with VSV-GP(Vero) were performed in different concentrations of EDTA (from 0.625 to 10 mM) (A) or with 5 mM MgEGTA (B). The remaining infectious virus titers were determined by plaque titration. Three independent experiments with two technical replicates were performed. Mean values are shown, and error bars indicate the SD.
