TABLE A1.
Results of the CS linear mixed model
| Parameter | Mean value (confidence interval) |
||
|---|---|---|---|
| Europe, UK | East Africa |
||
| Kenya | Uganda/Tanzania | ||
| Antibody concn 21 days postboost (in log10 ELISA units/ml) | |||
| Group MVA/Ad26 D29 | 3.94 (3.81, 4.07) | 3.80 (3.67, 3.93) | 3.69 (3.67, 3.93) |
| Group MVA/Ad26 D57 | 4.21 (4.08, 4.34) | 4.07 (3.94, 4.20) | 3.96 (3.94, 4.20) |
| Group Ad26/MVA D29 | 3.76 (3.63, 3.89) | 3.62 (3.49, 3.75) | 3.51 (3.49, 3.75) |
| Group Ad26/MVA D57 | 4.03 (3.90, 4.16) | 3.89 (3.76, 4.01) | 3.78 (3.76, 4.01) |
| Slope value before 150 days postboost (in log10 ELISA units/ml/30 days) | |||
| Group MVA/Ad26 D29 | −0.075 (−0.10, −0.048) | −0.20 (−0.23, −0.17) | −0.17 (−0.19, −0.14) |
| Group MVA/Ad26 D57 | −0.15 (−0.18, −0.12) | −0.28 (−0.31, −0.25) | −0.24 (−0.27, −0.21) |
| Group Ad26/MVA D29 | −0.075 (−0.10, −0.048) | −0.20 (−0.23, −0.17) | −0.17 (−0.19, −0.14) |
| Group Ad26/MVA D57 | −0.15 (−0.18, −0.12) | −0.28 (−0.31, −0.25) | −0.24 (−0.27, −0.21) |
| Slope value after 150 days postboost (in log10 ELISA units/ml/30 days) | |||
| Group MVA/Ad26 D29 | −0.038 (−0.049, −0.027) | −0.12 (−0.13, −0.11) | −0.089 (−0.10, −0.078) |
| Group MVA/Ad26 D57 | −0.086 (−0.098, −0.074) | −0.16 (−0.18, −0.15) | −0.14 (−0.15, −0.12) |
| Group Ad26/MVA D29 | −0.038 (−0.049, −0.027) | −0.12 (−0.13, −0.11) | −0.089 (−0.10, −0.078) |
| Group Ad26/MVA D57 | −0.086 (−0.098, −0.074) | −0.16 (−0.18, −0.15) | −0.14 (−0.15, −0.12) |