Table 1.
Demographic and Clinical Characteristics of Patients.
| Female, n = 46 (52.3%) | Male, n = 42 (47.7%) | Total, n = 88 | P Value, Female vs Male | |
|---|---|---|---|---|
| Age, years, mean (SD), (min-max) | 73.43 (9.90), (42-92) | 67.64 (13.19), (36-88) | 70.67 (11.88), (36-92) | .04a |
| 36-60 | 10 (21.7) | 17 (40.5) | 27 (30.7) | .07 |
| 61-79 | 22 (47.8) | 15 (35.7) | 37 (42) | .31 |
| ≥80 | 14 (30.4) | 10 (23.8) | 24 (27.3) | .45 |
| Vascular risk factors, n (%) | ||||
| Hypertension | 35 (76.1) | 24 (57.1) | 59 (67) | .19 |
| Diabetes mellitus | 18 (39.1) | 11 (26.2) | 29 (33) | .32 |
| Hyperlipidemia | 15 (32.6) | 10 (23.8) | 25 (28.4) | .61 |
| Atrial fibrillation | 26 (56.5) | 18 (42.9) | 44 (50) | .39 |
| Congestive heart failure | 8 (17.4) | 16 (38.1) | 24 (27.3) | .03a |
| Smoking | 1 (2.2) | 30 (71.7) | 31 (35.2) | <.001a |
| SBP (mm Hg), mean (SD), (min-max) | 154.34 (23.32), (80-220) | 152.50 (22.36), (110-200) | 153.46 (22.76), (80-220) | .64 |
| DBP (mm Hg), mean (SD), (min-max) | 84.89 (11.99), (60-120) | 86.78 (13.01), (70-120) | 85.79 (12.45), (60-120) | .65 |
| Blood glucose level (mg/dL), mean (SD), (min-max) | 158.36 (65.49), (89-363) | 159.25 (70.97), (78-345) | 158.88 (67.77), (78-363) | .54 |
| Mean platelet volume (fL), mean (SD), (min-max) | 8.96 (0.97), (7.2-11.1) | 8.59 (0.99), (6.4-11.3) | 8.78 (0.99), (6.4-11.3) | .50 |
| Platelet count (×103/μl) mean (SD), (min-max) | 240.67 (69.01) (107-398) | 230.95 (71.74) (108-409) | 236.03 (70.09) (107-409) | .59 |
| Stroke type according to TOAST, n (%) | ||||
| Large artery atherosclerosis | 4 (8.7) | 7 (16.7) | 11 (12.5) | .42 |
| Cardioembolism | 28 (60.9) | 25 (59.5) | 53 (60.2) | .89 |
| Lacunar infarct | 2 (4.3) | 1 (2.4) | 3 (3.4) | .60b |
| Other causes | - | 1 (2.4) | 1 (1.1) | - |
| Undetermined causes | 12 (26.1) | 8 (19) | 20 (22.7) | .45 |
| OTN time (minutes), mean (SD), (min-max) | 157.17 (46.68), (75-270) | 149.66 (54.49), (60-270) | 153.59 (50.40), (60-270) | .28 |
| NIHSS (pretreatment), mean (SD), (min-max) | 15.89 (5.54), (7-26) | 14.66 (5.77), (5-25) | 15.30 (5.65), (5-26) | .17 |
| NIHSS (after 24 hours), mean (SD), (min-max) | 11.34 (6.88), (1-23) | 11.23 (7.79), (0-26) | 11.29 (7.28), (0-26) | .95 |
| Cerebral hemorrhage, n (%) | ||||
| aICH, n (%) | 7 (15.2) | 5 (11.9) | 12 (13.6) | .42 |
| sICH, n (%) | 1 (2.2) | 2 (4.8) | 3 (3.4) | 1.00b |
| Mortality, n (%) | ||||
| 0-10 days | 3 (6.5) | 8 (19) | 11 (12.5) | .14 |
| 11-90 days | 5 (10.9) | 4 (9.5) | 9 (10.2) | .73b |
| 3-month mRS ≤ 2, n (%) | 24 (52.2) | 21 (50) | 45 (51.1) | .52 |
| p-HMCAS, n (%) | 9 (19.6) | 11 (26.2) | 20 (22.7) | .78 |
Abbreviations: aICH, asymptomatic intracerebral hemorrhage; DBP, diastolic blood pressure; min-max, minimum–maximum; mRS, modified Rankin scale; NIHSS, National Institute of Health Stroke Scale; OTN, onset-to-needle; p-HMCAS, proximal hyperintense middle cerebral artery sign; SBP, systolic blood pressure; SD, standard deviation; sICH, symptomatic intracerebral hemorrhage.
a <.05.
b Fisher exact test.