Table 1.
Type | Inhibitor BU | FVIII or FIX activity, % | Treatment | APTT: Acceleration Peak 1 | |||
---|---|---|---|---|---|---|---|
Time, second | Height, mAbs/s2 | Width, second | |||||
1 | Hemophilia A | <0.5 | 2.9 | On-demand | 58.2 | 20.4 | 178 |
2 | Hemophilia B | <0.5 | 3.6 | On-demand | 53.2 | 11.6 | 242 |
3 | Hemophilia A | <0.5 | <1.0 | Prophylaxis treatment | 89.7 | 51 | 37.5 |
4 | Hemophilia A | <0.5 | <1.0 | Prophylaxis treatment | 58.1 | 25.4 | 116 |
5 | Hemophilia A | <0.5 | 9.3 | On-demand | 49.2 | 18.4 | 379 |
6 | Hemophilia A | <0.5 | <1.0 | Prophylaxis treatment | 25.6 | 6.1 | 656 |
7 | Hemophilia B | <0.5 | 9.4 | On-demand | 41.4 | 9.8 | 736 |
8 | Hemophilia A | <0.5 | <1.0 | Prophylaxis treatment | 39.9 | 9.3 | 414 |
9 | Hemophilia B | <0.5 | <1.0 | On-demand | 62.7 | 28 | 161 |
10 | Hemophilia B | <0.5 | <1.0 | Prophylaxis treatment | 70.1 | 20.6 | 282 |
11 | Hemophilia A | <0.5 | 1.3 | On-demand | 52.5 | 15.2 | 15.6 |
12 | Pancreas cancer | 9.2 | 4.1 | Prednisolone | 65.1 | 19.5 | 31.6 |
13 | Hemophilia A | 5.6 | <1.0 | Bypass therapy | 125.6 | 24.2 | 14.4 |
14 | Hemophilia A | 93.2 | <1.0 | Bypass therapy | 69 | 62.1 | 33.5 |
15 | Hemophilia A | 76.2 | 2.3 | Bypass therapy | 68.4 | 23.1 | 114 |
16 | Hemophilia A | 95.1 | <1.0 | Bypass therapy | 114.4 | 113 | 24.5 |
Abbreviations: Abs, absorbance; APTT, activated partial thromboplastin time; BU, Bethesda unit; FVIII, factor VIII; FIX, factor IX.