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. 2019 Aug 28;4(4):e00454-19. doi: 10.1128/mSphere.00454-19

TABLE 5.

Metatranscriptomic MaAsLin enrichment results with relative abundance quartiles

Pathway Enrichment (CPM) for:
Coefficient Enrichment
group
P value FDR-corrected
P value
CDI Q1 CDI Q3 CDI+ Q1 CDI+ Q3
Valine leucine and isoleucine biosynthesis 9,514.11 15,392.90 5,648.81 8,337.13 −0.02054 CDI 0.008 0.146
Carbon fixation in photosynthetic organisms 10,333.69 14,029.93 6,935.82 8,324.76 −0.01236 CDI 0.008 0.146
Protein processing in endoplasmic reticulum 141.98 2,011.25 0.00 35.63 −0.0226 CDI 0.024 0.255
Glycine serine and threonine metabolism 17,065.75 24,255.21 13,585.16 17,256.03 −0.0103 CDI 0.025 0.255
Histidine metabolism 8,980.54 13,015.11 6,643.91 8,720.96 −0.01492 CDI 0.032 0.301
One-carbon pool by folate 8,894.96 14,537.30 6,096.51 8,641.10 −0.01285 CDI 0.056 0.390
C branched dibasic acid metabolism 5,504.79 9,086.76 4,008.12 6,235.85 −0.01223 CDI 0.059 0.392
Alpha-linolenic acid metabolism 0.00 207.16 693.91 1,265.72 0.02426 CDI+ 0.000 0.029
Bacterial chemotaxis 167.31 1,297.16 2,265.06 4,147.41 0.03489 CDI+ 0.000 0.029
Ascorbate and aldarate metabolism 526.98 2,203.76 3,161.59 6,267.15 0.03851 CDI+ 0.000 0.029
Ethylbenzene degradation 0.00 180.42 497.38 1,033.91 0.02145 CDI+ 0.001 0.029
Geraniol degradation 0.00 511.95 848.86 1,080.13 0.02247 CDI+ 0.001 0.029
Flagellar assembly 0.00 1,133.64 1,080.82 7,448.64 0.04871 CDI+ 0.001 0.029
Two-component system 14,066.55 21,493.11 25,306.60 40,448.82 0.06355 CDI+ 0.001 0.029
ABC transporters 28,206.82 44,320.11 48,815.21 59,718.37 0.05873 CDI+ 0.002 0.090
Sulfur relay system 2,878.55 6,146.67 6,467.43 7,358.35 0.02199 CDI+ 0.003 0.090
Linoleic acid metabolism 0.00 2.72 20.77 344.47 0.00917 CDI+ 0.003 0.090
Ether lipid metabolism 0.00 26.61 20.77 344.47 0.00915 CDI+ 0.003 0.090
Chlorocyclohexane and chlorobenzene degradation 0.00 21.93 125.99 506.71 0.01062 CDI+ 0.004 0.090
Biosynthesis of siderophore group nonribosomal
peptides
37.17 647.97 629.22 2,408.83 0.0236 CDI+ 0.005 0.120
Fluorobenzoate degradation 0.00 5.39 59.17 392.77 0.01066 CDI+ 0.009 0.165
Sulfur metabolism 4,620.15 9,094.60 7,747.39 11,277.50 0.02683 CDI+ 0.010 0.165
Toluene degradation 0.00 33.18 66.83 336.92 0.0094 CDI+ 0.014 0.206
Quorum sensing 14,686.72 18,688.39 18,603.71 23,100.57 0.02664 CDI+ 0.023 0.255
Phosphotransferase system 4,091.52 9,124.89 11,965.61 14,977.45 0.04152 CDI+ 0.029 0.279
Mitogen-activated protein kinase signaling pathway,
fly
0.00 410.01 403.97 1,096.53 0.01406 CDI+ 0.033 0.306
Lysine degradation 527.14 2,350.37 1,856.78 2,798.06 0.0183 CDI+ 0.042 0.345
Proteasome 0.00 5.99 0.00 228.25 0.00495 CDI+ 0.054 0.390
Biofilm formation, Pseudomonas aeruginosa 1.33 1,326.79 989.98 1,979.08 0.01642 CDI+ 0.055 0.390