Table 3.
The Numbers (Ratios) of Impaired/Decreased Platelet Aggregation on Different TKI Treatments.
İmatinib, n = 47 | Dasatinib, n = 15 | Nilotinib, n = 6 | P | |
---|---|---|---|---|
ADP (2 µM) | 12 (25.5%) | 5 (33.3%) | 1 (16.6%) | .71 |
ADP (6 µM) | 3 (6.4%) | 4 (26.6%) | 1 (16.6%) | .09 |
Epinephrine | 8 (17%) | 5 (33.3%) | 2 (33.3%) | .01 |
Collagen | 2 (4.2%) | 2 (13.3%) | 0 | .002 |
Ristocetin (1.25 mg/mL) | 2 (4.2%) | 0 | 0 | .63 |
Ristocetin (0.6 mg/mL) | 47 (100%) | 14 (93.3%) | 6 (100%) | .55 |
Abbreviations: ADP, adenosine diphosphate; TKIs, tyrosine kinase inhibitors.