Table 3.
Results LTA and Multiplate.a
| Platelet Function Tests | Smoking (n = 5) | Coffee (n = 5) | High-Fat Meal (n = 5) | Physical Exercise (n = 5) | Control (n = 6) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Before | After | Before | After | Before | After | Before | After | Before | After | |
| LTA | ||||||||||
| 1 mM NAAA | 87.0 (84.0-87.0) | 85.0 (81.0-87.0) | 81.0 (71.0-83.0) | 77.0 (75.0-81.0) | 83.0 (79.0-87.0) | 84.0 (83.0-84.0) | 82.0 (72.0-85.0) | 82.0 (81.0-83.0) | 80.5 (75.5-86.3) | 83.0 (79.8-84.0) |
| 2 µg/mL collagen | 81.0 (78.0-84.0) | 83.0 (81.0-88.0) | 84.0 (83.0-84.0) | 75.0 (71.0-83.0) | 85.0 (78.0-87.0) | 82.0 (810-86.0) | 84.0 (81.0-85.0) | 82.0 (81.0-83.0) | 81.0 (80.3-84.0) | 82.0 (75.8-87.5) |
| 5 µM ADP | 75.0 (75.0-79.0) | 78.0 (76.0-81.0) | 79.0 (75.0-83.0) | 75.0 (68.0-80.0) | 74.0 (73.0-76.0) | 83.0 (82.0-87.0) | 79.0 (79.0-81.0) | 75.0 (73.0-76.0) | 80.0 (77.5-83.3) | 77.0 (75.5-82.3) |
| 5 µM epinephrine | 79.0 (77.0-82.0) | 76.0 (72.0-78.0) | 79.0 (76.0-83.0) | 76.0 (74.0-77.0) | 79.0 (77.0-79.0) | 76.0 (76.0-87.0) | 81.0 (71.0-84.0) | 75.0 (73.0-76.0) | 79.0 (75.3-80.5) | 79.5 (76.0-82.3) |
| Multiplate | ||||||||||
| 6.4 µM ADP | 85.0 (84.0-102.0) | 87.0 (87.0-97.0) | 96.0 (96.0-110.0) | 95.0 (86.0-118.0) | 88.0 (82.0-89.0) | 90.0 (79.0-94.0) | 96.0 (95.0-100.0) | 105.0 (84.0-113.0) | 89.0 (85.3-91.5) | 84.0 (82.5-86.5) |
| 0.5 µM ASPI | 119.0 (110.0-120.0) | 126.0 (105.0-127.0) | 110.0 (99.0-118.0) | 107.0 (106.0-127.0) | 100.0 (76.0-110.0) | 102.0 (86.0-108.0) | 108.0 (86.0-108.0) | 105.0 (104.0-114.0) | 106.0 (98.8-110.3) | 99.0 (95.3-108.8) |
| 3.2 µg/mL collagen | 114.0 (105.0-116.0) | 112.0 (97.0-114.0) | 108.0 (105.0-118.0) | 127.0 (107.0-128.0) | 92.0 (73.0-94.0) | 95.0 (89.0-101.0) | 104.0 (97.0-120.0) | 119.0 (102.0-126.0) | 101.5 (95.3-107.0) | 95.5 (91.3-113.3) |
| 32 µM TRAP | 137.0 (137.0-147.0) | 140.0 (134.0-141.0) | 124.0 (123.0-125.0) | 125.0 (1230-130.0) | 114.0 (98.0-137.0) | 133.0 (122.0-137.0) | 118.0 (106.0-129.0) | 130.0 (122.0-147.0) | 118.5 (116.2-126.8) | 137.5 (116.5-148) |
Abbreviations: ADP, adenosine diphosphate; LTA, light transmission aggregometry; TRAP, thrombin receptor-activating peptide.
aFor LTA, the median amplitudes of the first and second blood collection with interquartile ranges are shown. For Multiplate, the median area under the curve (AUC) with interquartile ranges is shown before and after each parameter. No statistical differences were observed before and after each parameter.