Table 2.
Odds Ratios (ORs) and P Values of Thromboembolic Events in Univariable and Multivariable Analyses (Total Patients).
| Characteristics | No Thrombosis (%) | Thrombosis (%) | P Value (Univariable Analysis) | OR | 95% CI | P Value (Multivariable Analysis) |
|---|---|---|---|---|---|---|
| Age, years | ||||||
| ≥60 | 1118/2734 (40.9) | 21/28 (75.0) | <.001 | 8.608 | 1.845- | .006 |
| <60 | 1616/2734 (59.1) | 7/28 (25.0) | 1 | 40.152 | ||
| Gender | ||||||
| Male | 1907/2734 (69.8) | 20/28 (71.4) | 1.000 | |||
| Female | 827/2734 (30.2) | 8/28 (28.6) | ||||
| Smoking | ||||||
| Yes | 425/2720 (15.6) | 4/28 (14.3) | .913 | |||
| No | 2295/2720 (84.4) | 24/28 (85.7) | ||||
| ECOG | ||||||
| 0 | 1918/2717 (70.6) | 16/26 (61.5) | .162 | |||
| 1 | 686/2717 (25.2) | 7/26 (26.9) | ||||
| 2 | 113/2717 (4.2) | 3/26 (11.5) | ||||
| Histology | ||||||
| Clear cell type | 2144/2734 (78.4) | 19/28 (67.9) | .300 | |||
| Papillary type | 283/2734 (10.4) | 6/28 (21.4) | ||||
| Chromophobe | 213/2734 (7.8) | 2/28 (7.1) | ||||
| Others | 94/2734 (3.4) | 1/28 (3.6) | ||||
| T stage | ||||||
| 1 | 2078/2651 (78.4) | 12/27 (44.4) | <.001 | 1 | .923 | |
| 2 | 249/2651 (9.4) | 6/27 (22.2) | 1.265 | 0.211-7.588 | .797 | |
| 3 | 309/2651 (11.7) | 7/27 (25.9) | 0.666 | 0.102-4.364 | .671 | |
| 4 | 15/2651 (0.6) | 2/27 (7.4) | 0.930 | 0.047-18.398 | .962 | |
| N or M stage | ||||||
| N0M0 | 278/2734 (10.2) | 4/28 (14.3) | .523 | |||
| N+ or M+ | 2456/2734 (89.8) | 24/28 (85.7) | ||||
| Tumor thrombus | ||||||
| No thrombus | 2571/2714 (94.7) | 18/28 (64.3) | <.001 | 1 | 1.480-45.004 | .016 |
| Thrombus | 143/2714 (5.3) | 10/28 (35.7) | 8.160 | |||
| Tumor extrusion | ||||||
| Exophytic | 1242/2681 (46.3) | 11/26 (42.3) | .722 | |||
| Mesophytic | 738/2681 (27.5) | 9/26 (34.6) | ||||
| Endophytic | 701/2681 (26.1) | 6/26 (23.1) | ||||
| Preoperative Hb, g/dL | ||||||
| >16 | 219/2733 (8.0) | 2/28 (7.1) | 1.000 | |||
| ≤16 | 2514/2733 (92.0) | 26/28 (92.9) | ||||
| Preoperative platelet, /μL | ||||||
| >400 × 103 | 88/2732 (3.2) | 4/28 (14.3) | .013 | 2.232 | 0.503-9.907 | .291 |
| ≤400 × 103 | 2644/2732 (96.8) | 24/28 (85.7) | 1 | |||
| Preoperative NLR | ||||||
| ≥1.87 | 1358/2729 (49.8) | 19/28 (67.9) | .060 | |||
| <1.87 | 1371/2729 (50.2) | 9/28 (32.1) | ||||
| Preoperative CRP, mg/dL | ||||||
| >0.5 | 391/1680 (23.3) | 11/15 (73.3) | <.001 | 4.144 | 1.107-15.516 | .035 |
| ≤0.5 | 1289/1680 (76.7) | 4/15 (26.7) | 1 | |||
Abbreviations: CI, confidence interval; CRP, C-reactive protein; ECOG, Eastern Cooperative Oncology Group; Hb, hemoglobin; NLR, neutrophil-to-lymphocyte ratio.