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. Author manuscript; available in PMC: 2019 Aug 29.
Published in final edited form as: Biomed Pharmacother. 2019 Feb 20;112:108628. doi: 10.1016/j.biopha.2019.108628

Table 2.

Glucose analysis.

Normalization Method Whole Brain Normalization Method Cerebellum Normalization Method Pons Normalization Method
Structure Volume (cc) % Volume Slope (Z-score/ mg/dL glucose) STE Unadjusted p-values FDR Adjusted p-values Slope (Z-score/ mg/dL glucose) STE Unadjusted p-values FDR Adjusted p-values Slope (Z-score/ mg/dL glucose) STE Unadjusted p-values FDR Adjusted p-values
Basis Pontis 8/10 8.36 0.50% 0.003 0.002 0.168 0.269 5.00E-04 0.003 0.865 0.909
Cerebellar Hemisphere 116.3 6.96% 0.001 0.002 0.739 0.876 −0.007 0.005 0.143 0.226
8/10
Amygdala 4.1 0.2% −0.015 0.003 0.000 0.001 −0.011 0.007 0.114 0.534 −0.010 0.006 0.090 0.224
Globus Pallidus 5.3 0.3% −0.006 0.002 0.006 0.047 −0.008 0.006 0.179 0.534 −0.011 0.005 0.054 0.224
Hippocampus 8/10 5.1 0.3% −0.013 0.003 0.000 0.002 −0.010 0.006 0.124 0.534 −0.009 0.007 0.204 0.274
Inferior Occipital 18.0 1.1% −0.005 0.002 0.005 0.045 −0.008 0.006 0.164 0.534 −0.010 0.005 0.046 0.224
Gyrus
Inferior Temporal 47.1 2.8% −0.016 0.004 0.000 0.002 −0.007 0.005 0.194 0.534 −0.011 0.005 0.038 0.224
Gyrus
Medial Temporal Lobe 16.6 1.0% −0.005 0.002 0.007 0.048 −0.008 0.006 0.151 0.534 −0.011 0.006 0.055 0.224
8/10
Middle Orbital Gyrus 16.5 1.0% −0.006 0.002 0.005 0.045 −0.007 0.005 0.186 0.534 −0.010 0.005 0.046 0.224
Parietal Lobe 341.8 20.5% −0.007 0.002 0.004 0.042 −0.005 0.005 0.282 0.534 −0.009 0.005 0.064 0.224
Precentral Gyrus 60.8 3.6% −0.010 0.003 0.000 0.004 −0.006 0.005 0.258 0.534 −0.010 0.005 0.054 0.224
Postcentral Gyrus 68.7 4.1% −0.016 0.003 0.000 0.001 −0.007 0.005 0.204 0.534 −0.010 0.005 0.049 0.224
Posterior Cingulate 19.81 1.19% 0.006 0.005 0.222 0.341 0.000 0.003 0.971 0.971 −0.003 0.004 0.434 0.468
Gyrus
Posterior Cingulate 12.85 0.77% 0.004 0.004 0.300 0.401 −0.001 0.003 0.826 0.880 −0.004 0.004 0.361 0.400
Gyrus 8/10
Precuneus 59.31 3.55% 0.000 0.001 0.970 0.973 −0.005 0.004 0.289 0.534 −0.007 0.005 0.140 0.226
Angular Gyrus 75.2 4.5% −0.004 0.001 0.014 0.066 −0.005 0.005 0.282 0.534 −0.009 0.005 0.081 0.224
Hippocampus 9.8 0.6% −0.005 0.002 0.010 0.052 −0.008 0.006 0.153 0.534 −0.011 0.006 0.064 0.224
Posterior Orbital 6.7 0.4% −0.003 0.001 0.035 0.146 −0.006 0.005 0.242 0.534 −0.010 0.005 0.055 0.224
Gyrus
Superior Frontal Gyrus 79.7 4.8% −0.004 0.002 0.013 0.061 −0.006 0.005 0.263 0.534 −0.009 0.005 0.063 0.224
Superior Parietal 70.7 4.2% −0.004 0.001 0.010 0.052 −0.006 0.005 0.236 0.534 −0.009 0.005 0.073 0.224
Lobule
Supramarginal Gyrus 46.2 2.8% −0.004 0.002 0.009 0.052 −0.005 0.005 0.295 0.534 −0.009 0.005 0.064 0.224