Table 3.
Allelic and Genotypic Associations.a
| Polymorphisms | Allelic Frequencies | Genotypic Frequencies | ||||
|---|---|---|---|---|---|---|
| Case | Control | Allelic χ2/P Value | Case | Control | Genotypic χ2/P Value | |
| −174G>C | G = 0.73 | G = 0.80 | 4.79/.028 | GG = 0.51 | GG = 0.65 | 5.3/.021 |
| r-s22727026 | C = 0.27 | C = 0.20 | GC = 0.42 | GC = 0.30 | ||
| CC = 0.07 | CC = 0.05 | |||||
| −572G>C | G = 0.63 | G = 0.75 | 9.63/.001 | GG = 0.37 | GG = 0.59 | 13.74/.0002 |
| rs22726646 | C = 0.37 | C = 0.25 | GC = 0.51 | GC = 0.32 | ||
| CC = 0.12 | CC = 0.09 | |||||
| −597G>A | G = 0.86 | G = 0.85 | 0.13/.71 | GG = 0.75 | GG = 0.73 | 0.16/.68 |
| rs22726602 | C = 0.14 | C = 0.15 | GA = 0.23 | GA = 0.25 | ||
| AA = 0.02 | AA = 0.02 | |||||
aCase–control χ2 and P values for genotypic and allelic associations observed for −174G>C, −572G>C, and −597G>A analyzed in this study.