Table 4.
Association of Plasma IL-6 Levels With IL-Genotypes.a
| Genotype | N | IL-6 Levels,b Mean ± SD | P Value | Post Hoc P Value | ||
|---|---|---|---|---|---|---|
| GG vs C | GG vs C | GC vs C | ||||
| −174G>C | ||||||
| GG | 118 | 15.17 ± 10.95 | .0001 | .002 | .008 | .067 |
| GC | 73 | 21.04 ± 12.75 | ||||
| CC | 9 | 32.76 ± 14.80 | ||||
| −572G>C | GG vs C | GG vs C | GC vs C | |||
| GG | 99 | 13.8 ± 10.91 | .0001 | .001 | .002 | .99 |
| GC | 80 | 22.42 ± 13.10 | ||||
| CC | 21 | 21.99 ± 10.54 | ||||
| −597G>A | GG vs A | GG vs A | GA vs A | |||
| GG | 147 | 18.21 ± 12.83 | .28 | .999 | .19 | .17 |
| GA | 48 | 16.80 ± 10.90 | ||||
| AA | 5 | 27.4 ± 15.47 | ||||
Abbreviation: IL-6, interleukin 6.
aThe −174G>C and −572G>C single-nucleotide polymorphisms show association with IL-6 levels.
bIL-6 levels in pg/mL.