Table 5.
Association of Plasma IL-6 Levels With IL Genotypes Across Patients and Controls Under a Recessive Model and Adjusted for Alcohol, Smoking, Hypertension, HDL, LDL, and VLDL.
| Genotype | Total No. | Patient (IL-6 Levels,a Mean ± SD) N | Control (IL-6 Levels,a Mean ± SD) N | P Value |
|---|---|---|---|---|
| −174G>C | ||||
| GG | 123 | 25.3 ± 8.1 (55) | 6.87 ± 3.0 (68) | .311 |
| GC + CC | 77 | 32.7 ± 7.5 (45) | 8.69 ± 4.6 (32) | |
| −572G>C | ||||
| GG | 104 | 27.4 ± 6.6 (40) | 6.4 ± 2.8 (64) | .510 |
| GC + CC | 96 | 29.4 ± 9.7 (60) | 12.1 ± 6.1 (36) | |
| −597G>A | ||||
| GG | 148 | 28.9 ± 8.8 (75) | 7.3 ± 3.5 (73) | .321 |
| GA + AA | 52 | 27.6 ± 8.1 (25) | 8.7 ±5.2 (27) |
Abbreviation: IL-6, interleukin 6; HDL, high-density lipoprotein; LDL, low-density lipoprotein; VLDL, very-low-density lipoprotein.
aIL-6 levels in pg/mL.