Table 1.
Baseline Clinical and Laboratory Characteristics According to Thrombus Burden.
| Variable | Low Thrombus Burden, n= 140 | High Thrombus Burden, n=207 | P Value |
|---|---|---|---|
| Age, years | 55.7 (10) | 57.2 (13) | .267 |
| Sex, male % | 54 | 58 | .508 |
| Diabetes, % | 23.6 | 33.8 | .043 |
| Hypertension, % | 42.5 | 43.2 | .882 |
| Smoking, % | 42.1 | 44.9 | .459 |
| Dyslipidemia, % | 43.5 | 48 | .237 |
| Previous history of CAD, % | 21 | 20 | .893 |
| Family history of CAD | 11.4 | 21.7 | .014 |
| Systolic blood pressure, mm Hg | 128 (13) | 131 (20) | .600 |
| Heart rate, /min | 76.5 (16) | 74.7 (16) | .145 |
| C-reactive protein, mg/dL | 0.90 (0.04 -1.22) | 1.15 (0.09 -1.25) | <.001 |
| Albumin, g/dL | 4.1 (3.7-4.5) | 3.5 (3.1-4.5) | <.001 |
| CAR, ×100 | 24.4 (1.2-30.2) | 31.9 (2.2-31.3) | <.001 |
| Neutrophil–lymphocyte ratio | 5.8 (3.5-7.1) | 6.4 (4.4-8) | .004 |
| Hemoglobin, g/dL | 13 (11.5-14) | 12.5 (11.4-13.5) | .125 |
| White blood cell count, ×103/µL | 9.2 (2.5) | 9.7 (2.5) | .019 |
| Baseline troponin, mg/L | 5.5 (4) | 6.8 (4.7) | .009 |
| Platelet count, ×103/µL | 216 (76) | 218 (78) | .734 |
| LDL cholesterol, mg/dL | 138 (30) | 141 (32) | .328 |
| HDL cholesterol, mg/dL | 34.7 (80) | 33.3 (13) | .294 |
| Triglyceride, mg/dL | 193 (103) | 181 (97) | .262 |
| GFR, mL/min | 75 (18) | 77 (16) | .205 |
| EF,% | 45 (6) | 44 (9) | .090 |
| Previous medications, % | |||
| Aspirin | 30 | 20 | .057 |
| Statin | 16 | 15 | .881 |
| ACE inhibitors/ARB | 28 | 35 | .161 |
| β-Blocker | 12 | 11 | .867 |
| Infarct-related artery | |||
| LAD, n (%) | 35 | 27 | .233 |
| Cx, n (%) | 44 | 45 | |
| RCA, n (%) | 20 | 27 | |
| Multivessel disease, % | |||
| 1-Vessel | 60 | 46 | .025 |
| 2-Vessel | 30 | 35 | |
| 3-Vessel | 9 | 17 | |
| No reflow, % | 5.7 | 13 | .029 |
Abbreviations: CAD, coronary artery disease; CAR, C-reactive protein to albumin ratio; NLR, neutrophil to lymphocyte ratio; LDL, low-density lipoprotein; HDL, high-density lipoprotein; ACE, angiotensin converting enzyme; ARB, angiotensin receptor blocker; CCB, calcium channel blocker; OAD, oral antidiabetic drug.
a The normal cutoff value of troponin in our laboratory <0.04 mg/L.