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. 2019 Aug 29;14(8):e0221429. doi: 10.1371/journal.pone.0221429

Table 1. Antimicrobial classes, antimicrobial agents, concentration ranges, and susceptibility breakpoints for Campylobacter isolates.

Antimicrobial Class
Antimicrobial Agent Concentration Range (μg/mL) MIC Interpretive Standard (μg/mL)A
Susceptible Resistant
Aminoglycosides Gentamicin 0.12–32 ≤2 ≥4
Ketolides Telithromycin 0.015–8 ≤4 ≥8
Lincosamides Clindamycin 0.03–16 ≤2 ≥4
Macrolides Azithromycin 0.015–64 ≤2 ≥4
Erythromycin 0.03–64 ≤8 ≥16
Phenicols Florfenicol 0.03–64 ≤4 N/A
Quinolones Ciprofloxacin 0.015–64 ≤1 ≥2
Nalidixic acid 4–64 ≤16 ≥32
Tetracyclines Tetracycline 0.06–64 ≤4 ≥8

AIsolates were tested for antimicrobial susceptibility using an automated broth microdilution technique (Sensititre®). Minimum inhibitory concentration (MIC) interpretive standards of the Canadian Integrated Program for Antimicrobial Resistance Surveillance (for most antimicrobials) [15] or the Centers for Disease Control and Prevention (for telithromycin) [25] were used to classify isolates as susceptible or resistant (resistant plus intermediate).