Table 2. Cohen’s kappa test comparing detergent-enhanced RIME versus TBG1 LAMP.
| For all stage-1 and stage-2 HAT CSFs | |||
| HAT Stage | # CSF Samples | kappa Coefficient | 95% Confidence Interval |
| 1 | 73 | 0.92 | 0.82–1.00 |
| 2 | 77 | 0.90 | 0.80–1.00 |
| 1+2 | 150 | 0.91 | 0.84–1.00 |
| For all stage-1 and stage-2 HAT CSFs including non-HAT CSF controls | |||
| HAT Stage | # CSF Samples | kappa Coefficient | 95% Confidence Interval |
| 1 | 73 | 0.94 | 0.87–1.00 |
| 2 | 77 | 0.92 | 0.83–1.00 |
| 1+2 | 250 | 0.93 | 0.87–1.00 |
*After 60 min preincubation with Triton X-100 prior to LAMP assay