. 2019 Aug 29;14(8):e0221866. doi: 10.1371/journal.pone.0221866

Table 5. Levels of 7 parameters in patients receiving different chemotherapy regimens throughout chemotherapy.

Parameter	Regimen	Prechemotherapy	Prior to the last cycle of chemotherapy	6 m after chemotherapy
Parameter	Regimen	Mean±SD	Mean±SD	Mean±SD
TC	Anthracycline	5.09±1.09	5.25±1.15	4.93±0.80
	Taxane	5.10±1.09	5.18±0.89	4.87±1.07^*
	Anthracycline+taxane	5.10±1.09	5.19±1.02	5.05±1.05
TG	Anthracycline	1.68±0.81	2.14±1.52^*	2.13±2.05
	Taxane	1.60±1.00	2.04±1.13^*	2.00±1.91^*
	Anthracycline+taxane	1.68±0.98	2.21±1.56^*	1.85±1.12^*
LDL-C	Anthracycline	2.89±0.79	3.05±0.91	2.62±0.64^*
	Taxane	2.84±0.74	2.92±0.69	2.59±0.76^*^&
	Anthracycline+taxane	2.87±0.78	3.01±0.83^*	2.78±0.80
HDL-C	Anthracycline	1.39±0.41	1.26±0.29^*^&	1.38±0.36
	Taxane	1.35±0.32	1.24±0.34^*^&	1.34±0.35
	Anthracycline+taxane	1.32±0.27	1.16±0.27^*	1.34±0.30
HCY	Anthracycline	9.11±2.38	9.39±2.86	8.81±2.05
	Taxane	9.60±2.35	9.10±2.23^*	9.84±2.13^#
	Anthracycline+taxane	9.36±2.42	8.72±2.51^*	9.59±2.96
UA	Anthracycline	283.41±60.69	296.22±77.25^*	293.67±54.52
	Taxane	266.48±51.59	268.12±58.50^#	292.36±57.36^*
	Anthracycline+taxane	268.77±56.57	268.52±54.62^#	289.47±62.50^*
BMI	Anthracycline	22.27±2.55	22.37±2.67	22.43±2.74
	Taxane	22.46±2.86	22.92±2.92^*^#	22.66±2.89
	Anthracycline+taxane	22.50±2.60	22.89±2.88^*	22.85±2.77^*

TC: total cholesterol (mmol/L); TG: triglycerides (mmol/L); LDL-C: low-density lipoprotein cholesterol (mmol/L); HDL-C: high-density lipoprotein cholesterol (mmol/L); HCY: homocysteine (μmol/L); UA: uric acid (μmol/L); BMI: body mass index; 6 m: 6 months; SD: standard deviation

*: P<0.05 compared with baseline levels (prechemotherapy levels)

^#: P<0.05 compared with the group receiving the anthracycline chemotherapy regimen

^&: P<0.05 compared with the group receiving the anthracycline + taxane chemotherapy regimen