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. Author manuscript; available in PMC: 2019 Aug 29.
Published in final edited form as: Mol Cancer Ther. 2018 Apr 25;17(7):1540–1553. doi: 10.1158/1535-7163.MCT-17-0823

Figure 7.

Figure 7.

A combined treatment of oridonin with 5-FU or cisplatin inhibits cell growth. (A, B) The growth of KYSE410 and KYSE450 cells was determined after co-treatment with various concentrations of oridonin and 5-FU (1.2 μM) or cisplatin (1 μM) for 24, 48 or 72 h. The effect on growth was measured by MTT assay. (C-F) The effect of treatment with a combination of oridonin (5 μM) and 5-FU or cisplatin on anchorage-independent growth of KYSE410 and KYSE450 cells was evaluated. The asterisks (* p < 0.05, ** p < 0.001) indicate a significant decrease in colony number compared to 5 μM oridonin.