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. Author manuscript; available in PMC: 2019 Aug 29.
Published in final edited form as: Dev Cell. 2015 Feb 23;32(4):447–458. doi: 10.1016/j.devcel.2015.01.016

Figure 4. Neural activity influences oligodendrocyte plasticity.

Figure 4.

Schematic of the neural induced modification of oligodendrogenesis and the feedback loop from myelin plasticity enhancing neural-mediated behavior. In rodents, optogenetic induced electrical activity results in enhanced oligodendrogenesis resulting in enhanced swing speed on a Catwalk apparatus. Additionally, motor learning on a complex wheel requires new oligodendrogenesis. Mouse illustration provided and used with permission from Dr. Michelle Monje.