TABLE 10.

Contraindications to COCs89

ABSOLUTE CONTRAINDICATIONS

RELATIVE CONTRAINDICATIONS

•Lactation less than six weeks postpartum •Age >35 years and smoking >15 cigarettes/day •Hypertension (systolic >160 or diastolic >100) •Coronary artery disease/cerebrovascular disease •Deep venous thrombosis, pulmonary embolism, known thrombogenic mutations •Major surgery with prolonged immobilization •Valvular heart disease with complications (e.g., atrial fibrillation, pulmonary hypertension) •Migraine with aura or no aura if age >35 years •Current breast cancer •Diabetes with complications •Acute viral hepatitis, decompensated liver cirrhosis, liver tumor

•Lactation six weeks to six months postpartum •Age >35 years and smoking <15 cigarettes/day •Hypertension (systolic 140–160 or diastolic 90–100) •Multiple risk factors for cardiovascular disease; hyperlipidemia •Previous breast cancer longer than five years ago with no recurrence •Mild compensated liver cirrhosis, previous COC-induced cholestasis, gallbladder disease, concurrent medication with potential for transaminitis