Table 2.

Structural comparison between MMF-bound hGAPDH and others based on the DALI server hits

Protein	Species	Ligand	PDB code (chain)	r.m.s.d. (Å)	No. of aligned	Identity (%)	Z-score
GAPDH	Homo sapiens	NAD+	4wnc (A)	0.2	333	100	57.3
	Escherichia coli O157:H7	Apo	5o0v (A)	0.7	330	66	52.1
	Trypanosoma cruzi	BRZ	1k3t (A)	1.1	359	53	49.1
	Lactobacillus acidophilus	Apo	5j9g (A)	1.3	338	42	46.6
	Streptococcus agalactiae	NAD+, G3H	5jya (D)	1.3	343	45	46.1
	S. agalactiae	Apo	5jyf (B)	1.3	294	46	38.1

NAD⁺, nicotinamide-adenine-dinucleotide; BRZ, 6-(1,1-dimethylallyl)-2-(1-hydroxy-1-methylethyl)-2,3-dihydro-7h-furo[3,2-g]chromen-7-one; G3H, glyceraldehyde-3-phosphate.