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. 2019 Jul 16;42(8):579–588. doi: 10.14348/molcells.2019.0065

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© The Korean Society for Molecular and Cellular Biology. All rights reserved.

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Fig. 4 — (A) Comparison of AUROC between CMap and NGSEA for the ability to retrieve known drugs to treat colorectal cancer using a gene expression data set from patients with colorectal cancer (GSE9348). (B) The top 30 chemicals for colorectal cancer as predicted by NGSEA. The color code indicates how the anti-cancer effect on colorectal cancer was validated for each predicted chemical. The asterisk (*) indicates the two drugs tested in this study. (C) Cell viability in the HCT-116 cell line after treatment with various concentrations of budesonide. (D) Cell viability in the HT-29 cell line after treatment with various concentrations of budesonide.