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. 2019 Aug 29;8:e46831. doi: 10.7554/eLife.46831

Table 1. Cerebellar activations during acquisition and extinction.

Displayed are all clusters of ≥20 mm3. In each cluster, up to three maxima are listed separated by ≥8 mm. Corresponding activations for whole brain analysis are summarized in Supplementary file 1 Table 5.

Index Location
(lobule)
Side SUIT coordinates/mm Cluster size/mm3 pFWE TFCE
A) US post CS+ > no US post CS-: acquisition t-test, TFCE, p<0.05, FWE corr.
 1 Extended cluster left VI (8390), white matter (7950), left Crus I (7889), right VI (6404), right V (4250), left Crus II (4223), left V (4085), right Crus I (3457), right I-IV (2761), left I-IV (2529), right VIIIa (2432), right VIIIb (2244), left VIIb (1602), left VIIIb (1583), left VIIIa (1536), right VIIb (1467), vermal VI (1368), right IX (1330), vermal VIIIa (1307), right Crus II (1034), right dentate nuc. (921), vermal IX (804), left dentate nuc. (713), left IX (628), vermal VIIIb (474), vermal VIIb (236), right X (168), vermal Crus II (162), vermal X (120), left interposed nuc. (86), left X (70), right interposed nuc. (69), left fastigial nuc. (23), vermal Crus I (21), right fastigial nuc. (19)
Crus I Left −26 −74 −27 72355 0.001 5386.8
I-IV Left 0 −53 −24 0.001 5373.2
V Left -3 −62 −23 0.001 5032.2
 2 IX Left -5 −47 −51 39 0.025 1592.2
 3 IX Right 7 −49 −61 117 0.034 1435.8
b) CS+ > CS-: habituation t-test, TFCE, p<0.05 FWE corr.
no significant voxels
c) CS+ > CS-: acquisition t-test, TFCE, p<0.05, FWE corr.
 1 Extended cluster right Crus I (1506), right VI (1481), white matter (23), right V (16)
VI Right 35 −50 −31 3027 0.004 2256.6
VI Right 33 −60 −26 0.004 2174.7
Crus I Right 40 −57 −32 0.005 2082.8
 2 Extended cluster left Crus I (1658), left VI (727)
Crus I Left −44 −56 −33 2385 0.006 1911.7
Crus I Left −36 −53 −33 0.007 1851.3
Crus I Left −41 −64 −31 0.014 1629.8
 3 Extended cluster right VIIIa (287), right VIIIb (283), white matter (36), right VIIb (2)
VIIIb Right 28 −48 −49 608 0.019 1495.2
VIIIb Right 22 −54 −48 0.020 1483.1
VIIIa Right 29 −58 −47 0.037 1263.4
 4 Crus I Left −17 −76 −29 264 0.036 1278.4
 5 Crus I Left −34 −75 −25 46 0.047 1163.4
d) CS+ > CS-: extinction t-test, TFCE, p<0.05 FWE corr.
no significant voxels
e) no-US post CS+ > no US post CS-: acquisition t-test, TFCE, p<0.05, FWE corr.
 1 Extended cluster left Crus I (7688), left VI (4023), left Crus II (3373), white matter (1741), right I-IV (580), left VIIb (541), left dentate nuc. (474), left I-IV (472), vermal VIIIb (226), vermal IX (200), right interposed nuc. (163), vermal VIIIa (159), right dentate nuc. (92), left interposed nuc. (73), right V (70), left V (41), left IX (34), right fastigial nuc. (31), left VIIIa (30), vermal VI (9), right IX (9), vermal Crus I (8), left fastigial nuc. (8), vermal Crus II (2)
Crus I Left −17 −78 −25 20047 <0.001 4010.8
VI Left −25 −73 −26 <0.001 3912.9
Crus I Left −41 −68 −29 0.001 3633.1
 2 Extended cluster right Crus I (1313), right VI (750), white matter (66)
VI Right 30 −68 −27 2129 0.015 1484.6
VI Right 25 −73 −22 0.018 1422.4
Crus I Right 45 −65 −27 0.019 1384.5
 3 Crus II Right 15 −79 −33 42 0.047 1079.1
f) no-US post CS+ > no US post CS-: extinction t-test, TFCE, p<0.05, FWE corr.
 1 Crus I Left −14 −72 −35 273 0.016 1416.9