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. Author manuscript; available in PMC: 2019 Aug 29.
Published in final edited form as: Nature. 2019 Jul 22;572(7769):382–386. doi: 10.1038/s41586-019-1440-8

Extended data Fig. 8. Cryo-EM model refinement.

Extended data Fig. 8

a) FSC between model and the map and cross-validation of the model fitting. FSC0.5 = 4.3 Å for the model vs map (sum). Half-map cross validation procedure22 does not show significant overfitting in the refined model. b) Local resolution analysis (Relion) shows variation in the map resolution ranging from 3.9 to 5.1 Å. c) Overview of the model fitting into the map in the same orientation as in b. d) An example of the cryo-EM map quality with the atomic model fitted in, showing clear density for side chains.