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. 2019 Aug 8;6(5):e598. doi: 10.1212/NXI.0000000000000598

Figure 4. Baseline NfL levels and post IAHSCT MRI outcomes.

Figure 4

A baseline serum Nf-L >28.24 pgml-1 (red lines, n = 11) compared to <28.24 pgml-1 (blue lines, n = 12) was associated with (A) greater T1 lesion volumes (p = 0.017), (B) greater T2 lesion volumes (p = 0.0009) and (C) reduced MRI spectroscopy NAA/Cr ratio (p = 0.0038). The interaction of NfL over time was only significant for T1, accounting for 0.9% of the variability; patients with high baseline NfL had slightly more T1 lesion volume accrual post-treatment. Error bars represent the standard error. NfL = neurofilament light chain.