Skip to main content
. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Expert Rev Hematol. 2019 Jul 16;12(9):773–785. doi: 10.1080/17474086.2019.1640599

Table 1.

BERLIN definition for ARDS [18]

Timing Within 1 week of a known clinical insult or new or worsening respiratory symptoms
Chest imaging Bilateral opacities—not fully explained by effusions, lobar/lung collapse, or nodules
Origin of edema Respiratory failure not fully explained by cardiac failure or fluid overload
Need objective assessment (e.g, echocardiography) to exclude hydrostatic edema if no risk factor present
Oxygenation
 Mild 200 mm Hg < PaO2/FIO2 ≤ 300 mm Hg with PEEP or CPAP ≥5 cm H2O*
 Moderate 100 mm Hg < PaO2/FIO2 ≤ 200 mm Hg with PEEP ≥5 cm H2O*
 Severe PaO2/FIO2 ≤ 100 mm Hg with PEEP ≥5 cm H2O*
*

Altitude Modification = (300 mm Hg) X (Measured Barometric Pressure mmHg/760 mmHg)

PEEP Modifications: The PEEP ≥ 5 cm H2O or CPAP ≥ 5 cm H2O may not be required for the definition of TRALI.