Table I.
Training Dataset |
Testing Dataset |
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
No recurrence | Metastatic-lethal | No recurrence | Metastatic-lethal | |||||||||||
n = 157 |
n = 212 |
n = 110 |
n = 76 |
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No. | % | Mean (SD) | No. | % | Mean (SD) | P-valuea | No. | % | Mean (SD) | No. | % | Mean (SD) | P-valuea | |
Age at diagnosis (years) | 64.9 (6.6) | 65.4 (6.4) | 0.5 | 64.0 (7.2) | 62.7 (7.8) | 0.3 | ||||||||
CAPRA-S score | 4.3 (3.0) | 6.6 (3.1) | <0.01 | 5.1 (2.0) | 7.0 (2.3) | <0.01 | ||||||||
Gleason score | ||||||||||||||
≤ 6 | 28 | 17.8 | 6 | 2.8 | <0.01 | 12 | 10.9 | 0 | 0 | <0.01 | ||||
7 | 95 | 60.5 | 76 | 35.8 | 58 | 52.7 | 21 | 42.1 | ||||||
8–10 | 34 | 21.7 | 130 | 61.3 | 40 | 36.4 | 44 | 57.9 | ||||||
Pathologic stageb | ||||||||||||||
Local | 83 | 52.9 | 58 | 27.4 | <0.01 | 61 | 55.5 | 16 | 21.1 | <0.01 | ||||
Regional | 74 | 47.1 | 154 | 72.6 | 49 | 44.5 | 60 | 78.9 | ||||||
PSA (ng/mL) at diagnosis | ||||||||||||||
< 4.0 | 17 | 10.8 | 21 | 9.9 | 0.03 | 5 | 4.5 | 7 | 9.2 | 0.2 | ||||
4.0–9.9 | 79 | 50.3 | 80 | 37.8 | 62 | 56.4 | 31 | 40.8 | ||||||
10.0–19.9 | 31 | 19.7 | 44 | 20.8 | 25 | 22.7 | 21 | 27.6 | ||||||
≥ 20 | 26 | 16.6 | 60 | 28.3 | 18 | 16.4 | 17 | 22.4 |
Based on a t-test (age), chi-square or Fisher’s exact test (categorical variables).
Local stage = pT2, N0/NX, M0; regional stage = pT3/T4 and/or N1, M0.