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. 2019 Aug 16;11(8):454–471. doi: 10.4253/wjge.v11.i8.454

Table 2.

Published comparative studies regarding fine needle biopsy needles performance in terms of diagnostic yield

Ref Study design N°Lesions, pan-creatic Rose Needles Gauge Diagnostic yield, % Sample adequacy, % Comments
[64] Cohort (201) No Opposing bevel vs reverse bevel 22-25 vs 20-22-25 71 vs 90 87 vs 99 Opposing bevel needle resulted superior
[65] Cohort 194 (100) Only in 12% of cases Franseen vs fork tip 22 64 vs 85 The use of ROSE is a confounding factor Fork tip seems superior, but the study lack of methodology
[66] RCT (50) Yes Franseen vs fork tip 22 > 90%, equivalent 94 vs 98 Equivalent
[67] Cohort (66) Procore 22 vs 25 87.5 vs 82.1 98 vs 95 Equivalent

RCT: Randomized clinical trial; ROSE: Rapid on site evaluation.