Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Structures of BACE inhibitors from peptidomimetics to NB‐360. Fully peptidic hydroxyethylene compound OM99‐2 occupying binding subsites from P4 to P4′ (Hong et al., 2000), peptidomimetic ethanolamine NB‐216 (Lerchner et al., 2010), cyclic ethanolamine 11c (Rueeger et al., 2013) occupying subsites P3, P1, and P2′, and cyclic amidine NB‐360 (Neumann et al., 2015) occupying P1 and P3. Interaction sites with catalytic aspartates are marked in blue
