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Summary of cluster-wise comparison and validation
| Comparison | Number of Differentially Methylated CpGs in study cohort (# CpGs on 450k Chip) | Significant in Validation Set (FDR < 0.1) | ΔBeta R-squared CLUES vs. Validation |
|---|---|---|---|
| Cluster S1 vs M | 53 (28) | 21 | 0.94 |
| Cluster S2 vs S1 | 18 (8) | 6 | 0.96 |
| Cluster S2 vs M | 247 (122) | 105 | 0.94 |
Rows indicate individual pairwise comparisons as performed using the nestedF method in Limma
