Table 1.

The analysis of single nucleotide polymorphisms (SNPs).

SNP	Location	p value for HWE	Genotype	All			Male			Female
				No.	% in with MAC-LD	p value	No.	% with MAC-LD	p value	No.	% with MAC-LD	p value
rs1792773	CARD17	0.4726	TT	41	21 (51)	0.831	20	10 (50)	0.546	21	11 (52)	0.741
	5′ UTR		TC	120	56 (47)		49	18 (37)		71	38 (54)
			CC	64	29 (45)		31	14 (45)		33	15 (46)
rs2276405	AIM2	0.6921	TC	26	13 (50)	0.613	12	7 (58)	0.222	14	6 (43)	0.463
	Exonic stop gain		CC	198	93 (47)		88	35 (40)		110	58 (53)
rs34298354	NLRP3	0.6985	CT	25	13 (56)	0.345	16	6 (38)	0.691	9	8 (89)	0.019
	Exonic synonymous		CC	200	92 (46)		84	36 (43)		116	56 (48)
rs3806268	NLRP3	0.7203	AA	77	32 (42)	0.096	30	11 (37)	0.515	47	21 (45)	0.153
	Exonic		GA	104	57 (55)		48	23 (48)		56	34 (61)
	synonymous		GG	44	17 (39)		22	8 (36)		22	9 (41)
rs7525979	NLRP3	0.9995	CC	166	79 (48)	0.511	71	30 (42)	0.340	95	49 (52)	0.589
	Exonic		CT	54	24 (44)		25	9 (36)		29	15 (52)
	synonymous		TT	4	3 (75)		4	3 (75)		0
rs3804099	TLR2	0.6884	TT	106	54 (51)	0.582	47	24 (51)	0.088	59	30 (51)	0.094
	Exonic		TC	100	44 (44)		42	17 (41)		58	27 (47)
	synonymous		CC	18	8 (44)		10	1 (10)		8	7 (88)
rs3804100	TLR2	0.1096	CC	10	2 (20)	0.224	7	0	0.022	3	2 (67)	0.657
	Exonic		CT	97	45 (46)		40	14 (35)		57	31 (54)
	synonymous		TT	117	59 (50)		52	28 (54)		65	31 (48)
rs5743705	TLR2	0.6776	CT	25	13 (52)	0.603	11	5 (46)	0.806	14	8 (57)	0.637
	Exonic synonymous		CC	200	93 (47)		89	37 (42)		111	56 (51)

Genotyping missing: 1 in rs2276405, 1 in rs3804100, 1 in rs3804099, 1 in rs7525979.

Abbreviation: HWE, Hardy Weinberg Equilibrium.