Table 3.
Biological parameters according the normo- or hypercalcemia-associated PJP forms.
| Normocalcemic PJP recipients (n = 31) | Hypercalcemic PJP recipients (n = 18) | P-value | |
|---|---|---|---|
| Serum calcium levels, mean ± SD (mg/dL) | |||
| Annual consultation (3 to 12 months before PJP) | 9.1 ± 1.1 | 9.8 ± 0.8 | 0.01 |
| Preceding medical visit (1 to 3 months before PJP) | 9.0 ± 1.1 | 9.8 ± 0.7 | 0.007 |
| Day-0 of hospitalization | 8.9 ± 1.2 | 11.9 ± 1.6 | <0.001 |
| PJP diagnosis (calcium serum peak) | 9.6 ± 0.6 | 12.6 ± 1.6 | <0.001 |
| % of serum calcium increase*, median [Q1; Q3] | 4.1 [1.1; 8.7] | 31.2 [16.2; 43.5] | <0.001 |
| End of PJP treatment | 9.0 ± 0.9 | 9.8 ± 0.8 | 0.003 |
| Next medical visit (2 to 6 months after PJP resolution) | 9.1 ± 0.8 | 9.8 ± 0.5 | 0.004 |
| Serum phosphorus levels, mean ± SD (mg/dL) | |||
| Annual consultation (3 to 12 months before PJP) | 3.3 ± 0.1 | 2.9 ± 0.8 | 0.16 |
| PJP diagnosis | 3.6 ± 0.1 | 3.7 ± 0.1 | 0.84 |
| Next medical visit (2 to 6 months after PJP resolution) | 3.5 ± 0.7 | 3.5 ± 0.1 | 0.97 |
| Serum PTH levels, mean ± SD (pg/mL) | |||
| Annual consultation (3 to 12 months before PJP) | 194 ± 21.8 | 179 ± 12.0 | 0.76 |
| Preceding medical visit (1 to 3 months before PJP) | 215 ± 14.2 | 216 ± 19.0 | 0.98 |
| PJP diagnosis | 86.6 ± 12.5 | 34.7 ± 34.0 | 0.41 |
| End of PJP treatment | 147 ± 61.8 | 137 ± 98.9 | 0.80 |
| Next medical visit (2 to 6 months after PJP resolution) | 173 ± 16.1 | 288 ± 47.2 | 0.49 |
| Serum 25-hydroxy-vitamin D levels, mean ± SD (ng/mL) | |||
| Annual consultation (3 to 12 months before PJP) | 22.4 ± 9.6 | 30.9 ± 6.9 | 0.002 |
| PJP diagnosis | 14.2 ± 8.6 | 28.1 ± 8.8 | 0.008 |
| End of PJP treatment | 30.3 ± 7.9 | 24.2 ± 7.7 | 0.12 |
| Next medical visit (2 to 6 months after PJP resolution) | 28.4 ± 10.2 | 26.9 ± 11.0 | 0.74 |
| Serum 1,25-hydroxy-vitamin D levels, mean ± SD (pg/mL) | |||
| PJP diagnosis | 46.7 ± 44.4 | 124 ± 61.7 | 0.06 |
| End of PJP treatment | 46.0 ± 1.4 | 27.8 ± 23.2 | 0.15 |
| Graft function | |||
| Annual consultation (3 to 12 months before PJP), eGFR (MDRD, ml/min/1.73 m2) | 39.4 ± 16.8 | 42.0 ± 18.0 | 0.62 |
| Next medical visit (2 to 6 months after PJP), eGFR (MDRD, ml/min/1.73 m2) | 37.1 ± 17.9 | 38.6 ± 10.9 | 0.76 |
| Urine calcium-to-creatinine-ratio, median [Q1; Q3] (mg/mg) | |||
| Annual consultation (3 to 12 months before PJP) | 0.03 [0.02; 0.06] | 0.02 [0.01; 0.07] | 0.67 |
| PJP diagnosis | 0.05 [0.02; 0.07] | 0.28 [0.16; 0.39] | 0.001 |
*Serum calcium peak compared to its reference level measured during the previous medical visit (1 to 3 months before PJP).