Skip to main content
. 2019 Aug;24(8):1637–1643. doi: 10.1016/j.drudis.2019.03.004

Table 2.

Concentration (mean ± SEM, n = 6) of dexamethasone in various eye tissues 2 h after topical administration of 50 μl of aqueous 1.5% (w/v) dexamethasone eyedrops containing dexamethasone–γ-cyclodextrin complex microsuspension to rabbits

graphic file with name fx1.gif

The drug was administered to the left eye and the drug concentration determined in both eyes. The term topical denotes how much the topical absorption contributed to the dexamethasone level in a given tissue (i.e., the difference of the left and right eye concentrations). The plasma concentration at 2 h was determined to be 35 ± 16 ng/ml [27].