Fig. 5.
Cortical porosity.
(A) Transverse and anterior-posterior micro-CT images showing cortical bone porosity in the mid-femoral diaphysis of male P70 Pyy KO and WT mice; bars = 200 μm. Graphs show mean canal diameter (Ca.Dm) and cortical porosity (Ct.Po) (Pore volume/Cortical bone volume (Po·V/Ct.V)) (mean ± SEM, n = 6 per genotype, **P < 0.01 versus WT; unpaired t-test).
(B) Micro-CT images showing cortical bone porosity in distal-femoral diaphysis of male P70 Pyy KO and WT mice; bars = 200 μm. Graphs show mean canal diameter (Ca.Dm) and cortical porosity (Ct.Po) (mean ± SEM, n = 6 per genotype, ***P < 0.001 versus WT; unpaired t-test).