Figure 6.

Normal proliferation but increased apoptosis of Oga^Vav-Cre bone marrow progenitors. (a) Percentage of LSK cells in the indicated cell cycle stage from each genotype was measured by DAPI staining and quantified by flow cytometry. Representative flow cytometric analysis can be found in Supplemental Fig. S3a. (b) Apoptosis was determined for the indicated genotypes and cell populations, by Annexin V positive and PI negative staining quantified by flow cytometry analysis. Representative flow cytometric analysis can be found in Supplemental Fig. S3b. Black bars represent wildtype and blue bars represent Oga^Vav-Cre. N = 3, error bars represent standard deviation, *p < 0.05, **p < 0.01 as determined by t-test.