Table 1.

The Effects of PDTC on the Parameters of Activation, Inactivation, and Recovery of Na_v1.7 Channels in HEK293 Cells

	Activation		Inactivation		Recovery
	V0.5	k	V0.5	k	τ
Control	−33.6 ± 3.4	5.7 ± 1.7	−77.6 ± 2.5	5.4 ± 0.2	4.5 ± 0.8
PDTC	−34.8 ± 3.6	6.6 ± 1.0	−84.0 ± 2.3a	5.1 ± 0.4	9.2 ± 3.3b

Mean values were derived from Boltzmann equation fits of individual data sets as described in the Methods.

^ap < 0.001 vs. corresponding control. Two-tailed paired student t test. Data expressed as mean ± SD.

^bp < 0.01