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miR-140-5p, miR-140-3p, and miR-146a Counteract IL-1β- and TNF-α-Induced Inflammation
(A) qRT-PCR analysis of IL6, IL8, IL1β, MMP13, and ADAMTS5 mRNA levels in response to overexpression of the three miRs followed by 24 h stimulation with IL-1β and TNF-α in chondrocytes from three donors. Error bars represent a 95% confidence interval from technical triplicates. (B) Western blot analysis of IL-6 and IL-8 in the same three donors. ACTB was used as loading control.
