TABLE 3.
Antibiotic | Total (n = 244) | M. abscessus subsp. abscessus pulmonary disease (n = 185) | M. abscessus subsp. massiliense pulmonary disease (n = 59) | ||||||
Adjusted ORa | 95% CIa,b | P-value | Adjusted OR | 95% CI | P-value | Adjusted OR | 95% CI | P-value | |
Clarithromycin | 0.588 | 0.290–1.194 | 0.142 | 0.425 | 0.191–0.945 | 0.036 | 1.460 | 0.214–9.962 | 0.699 |
Azithromycin | 1.558 | 0.844–2.877 | 0.156 | 2.339 | 1.141–4.794 | 0.020 | 0.295 | 0.061–1.418 | 0.128 |
Amikacin | 3.275 | 1.221–8.788 | 0.018 | 5.911 | 1.247–28.012 | 0.025 | 15.023 | 1.294–174.400 | 0.030 |
Imipenem | 2.078 | 1.151–3.753 | 0.015 | 2.050 | 1.018–4.126 | 0.044 | 1.357 | 0.280–6.575 | 0.705 |
Meropenem | 1.218 | 0.390–3.806 | 0.735 | 1.787 | 0.486–6.574 | 0.382 | 0.341 | 0.026–4.487 | 0.413 |
Cefoxitin | 1.121 | 0.659–1.908 | 0.672 | 1.253 | 0.656–2.394 | 0.495 | 0.610 | 0.133–2.795 | 0.524 |
Linezolidc | 2.231 | 1.078–4.616 | 0.031 | 2.875 | 1.221–6.772 | 0.016 | 1.286 | 0.189–8.746 | 0.797 |
Tigecycline | 2.040 | 1.079–3.857 | 0.028 | 1.971 | 0.931–4.173 | 0.076 | 2.614 | 0.291–23.514 | 0.391 |
Doxycycline | 0.599 | 0.260–1.380 | 0.229 | 0.628 | 0.222–1.772 | 0.379 | 0.408 | 0.053–3.147 | 0.390 |
Minocycline | 0.992 | 0.399–2.467 | 0.986 | 0.691 | 0.206–2.315 | 0.549 | 1.312 | 0.116–14.876 | 0.827 |
Moxifloxacinc | 0.695 | 0.372–1.300 | 0.255 | 0.866 | 0.393–1.908 | 0.720 | 1.495 | 0.303–7.388 | 0.622 |
Levofloxacinc | 0.474 | 0.193–1.162 | 0.103 | 0.453 | 0.142–1.445 | 0.181 | 0.242 | 0.032–1.857 | 0.172 |
Ciprofloxacin | 1.026 | 0.372–2.831 | 0.960 | 1.155 | 0.330–4.039 | 0.822 | 0 | 0 | 0 |
aOR, odds ratio; CI, confidence interval. bAdjusted for age, sex, body mass index, and radiographic findings. cAdministered orally and/or intravenously.