FIGURE 4.
The effect of isoflurane on performance in the Morris Water Maze (MWM) test. The latency of rats to find the hidden platform in the MWM on postnatal days (P) 28–32, Group I (1.5% isoflurane, 6 hours) compared with Group C (50% oxygen, 6 hours). The isoflurane exposure had no significant effect on the latency to find the platform compared with the control group. Data are presented as mean ± standard deviation of the two trials for each day (n = 16/group). Group C versus Group I on days 1, 2, 3, 4, and 5 were p = 0.984, p = 0.945, p = 0.258, p = 0.729, and p = 0.999, respectively. The p values were determined by two-way analysis of variance followed by Tukey’s post hoc test.