Fig. 4 -.

Pyramid plot of microbiome-associated gut metabolic pathways (KEGG). Pyramid plot displaying the number of microbiome-associated gut metabolic pathways (KEGG) associated with cancer compared with no cancer on biopsy (Kendell’s Tau for ordinal assessment, p = 0.01). Pyramid plot in which the X axis is the number of cases (individual patients) and the Y axis is the number of aberrant microbiome metabolic profiles. The 10 important microbiome PICRUSt pathways are represented, and the asterisk (*) indicates those important on the LASSO regression analysis.

KEGG = Kyoto Encyclopedia of Genes and Genomes; LASSO = least absolute shrinkage and selection operator; PICRUSt = Phylogenetic Investigation of Communities by Reconstruction of Unobserved States.