Figure 3: Formation of cataracts in LensΔGlut1 mice.
A. Images of 3-month-old LensΔGlut1 (a,a’) and 5-month-old LensΔGlut1Het (b,b’) demonstrate presence of cataracts in 3-month-old LensΔGlut1 mice but not in 5-month-old LensΔGlut1Het mice. In the SD-OCT image, the opacity is observed as hyper reflectivity which was observed in the LensΔGlut1 (Aa’) but not in the LensΔGlut1Het (Ab’) B. Western blot of lysates from lens epithelium of control and LensΔGlut1Het mice. CO: Cornea, LE: Lens epithelium, LF: Lens fiber cells.