Table 10.

Antinausea/vomiting medication options in pediatric migraine.

Drug	Dose	Toxicity
Prochlorperazine	Oral Child: 10–13 kg: 2.5 mg every 12–24 h Child: 13–18 kg: 2.5 mg every 8–12 h, max 10 mg/day Child: 18–40 kg: 2.5 mg every 8 h, or 5 mg every 12 h Intravenous Child: 0.1–0.15 mg/kg/dose	Sedation Dystonic reaction
Promethazine	Oral or Rectal Child: 0.25–1 mg every 4–6 h	Sedation Dystonic reaction
Ondansetron	Oral 4–8 mg every 8 h <15 kg: 0.2 mg/Kg 15–30 kg: 4 mg >30 kg: 4–8 mg	Sedation Dystonic reaction