Table 9.

Abortive therapies for pediatric migraine.

Drug	Usual Dosage
Ibuprofen	10 mg/kg every 6–8 h Age > 12 y to adult: 400–600 mg every 6 h Max: 2,400 mg/day
Naproxen sodium	5-7 mg,kg every 8–12 h Age > 13 y to adult: 250–500 mg every 8 h Max: 1,250 mg/day
Acetaminophen	10–15 mg/kg every 4–6 h Age > 13y to adult: 650–1,000 mg every 6-8 h Max: 3,000 mg/day
Rizatriptan	Children < 40 kg: 5 mg PO once Children > 40 Kg: 10 mg PO once Max: 30 mg/day (propranolol will increase serum concentration of rizatriptan)
Zolmitriptan	Nasal Children > 12 y: 2.5–5 mg IN once Max: 10 mg/day Oral (tablet or ODT) Max: 10 mg/day
Sumatriptan	Nasal Age 4–6 y: 5 mg Age7–11 y: 10 mg Age > l2 y:20 mg Subcutaneous Child: 0.06 mg/kg, age > 12 y: 6 mg Oral Child: 1 mg/kg, max 50 mg/day
Almotriptan	Age > 12 y:6.25–12.5 mg PO, may repeat once in 2 h Max: 25 mg/day
Sumatriptan/naproxen	Age 12–17 y: 1 tablet 10 mg sumatriptan/60 mg naproxen, max dose 85 mg sumatriptan/500 mg naproxen

IN, Intranasal; Max, Maximum; ODT, Orally disintegrating tablet; PO, oral.