TABLE 2.
Association of strength and variability of complex-network measures with the NCI score and symptom severity in PTSD (PCL5 score) and PCS (NSI score).
Complex network measure | Path (Integration) or node (Segregation) |
Symptom severity score |
Behavioral measure |
|
Neurocognitive | ||||
PCL5 score | NSI score | Composite | ||
(PTSD) | (PCS) | Index (NCI) | ||
Static functional integration measures | ||||
Shortest path length | L_MFG → L_Insula | –0.6902 | –0.6756 | 0.6589 |
L_Insula → L_Amygdala | 0.6822 | 0.6759 | –0.6298 | |
L_Amyg → R_Hippocampus | 0.6535 | 0.6930 | –0.6389 | |
R_Hippocampus → L_Precuneus | 0.6990 | 0.6580 | –0.3545 | |
Edge betweenness | L_MFG → L_Insula | –0.6704 | –0.6853 | 0.5871 |
L_Insula → L_Amygdala | 0.7370 | 0.6868 | –0.5303 | |
L_Amyg → R_Hippocampus | 0.7080 | 0.6372 | –0.3956 | |
R_Hippocampus → L_Precuneus | 0.7156 | 0.6669 | –0.4193 | |
Variance of dynamic functional integration | ||||
Shortest path length | L_MFG → L_Insula | –0.7532 | –0.7327 | 0.6704 |
L_Insula → L_Amygdala | –0.7579 | –0.7382 | 0.6748 | |
L_Amyg → R_Hippocampus | –0.7541 | –0.7358 | 0.6709 | |
R_Hippocampus → L_Precuneus | –0.8520 | –0.7737 | 0.4579 | |
Edge betweenness | L_MFG → L_Insula | –0.7330 | –0.7287 | 0.6672 |
L_Insula → L_Amygdala | –0.7358 | –0.7260 | 0.6586 | |
L_Amyg → R_Hippocampus | –0.7326 | –0.7264 | 0.6590 | |
R_Hippocampus → L_Precuneus | –0.8513 | –0.7776 | 0.4619 | |
Static functional segregation measures | ||||
Clustering Coefficient | L_MFG | –0.6859 | –0.6685 | 0.6245 |
Local Efficiency | L_MFG | –0.7013 | –0.6990 | 0.6826 |
L_Insula | 0.6527 | 0.6550 | –0.6290 | |
Dynamic functional segregation measures | ||||
Clustering Coefficient | L_MFG | –0.7478 | –0.7271 | 0.6538 |
L_Insula | –0.7412 | –0.7204 | 0.6533 | |
Local Efficiency | L_MFG | –0.7524 | –0.7324 | 0.6692 |
Table presents the correlation values (R-value), which were significant with p < 0.05 Bonferroni corrected.