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. 2019 Aug 23;7:205. doi: 10.3389/fbioe.2019.00205

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Copyright © 2019 Hosoyama, Lazurko, Muñoz, McTiernan and Alarcon.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Self-assembling angiogenic peptide hydrogel. (A) Schematic illustrating the structure of the the multi-domain peptide comprising the VEGF mimic QK sequence and its assembly into a β-sheet. (B) Visible macroscale vessels apparent within the explant materal 7 days post injection. (C) Massons's Trichrome and (D) HandE staining showing infiltration of scaffolds and presence of blood vessels with red blood cells [arrows] at 1 week post injection; scale bar 100 μm. Adapted with permission from Kumar et al. (2015). Copyright 2015 American Chemical Society.