Table 2:
Homozygous Risk Allele Frequencies in the American Indian (AI) and Rancher (R) population with and without Hypertensive Retinopathy.
| SNP | Alleles | Effect | AI Normal (n =23) |
AI HTR (n=21) |
R Normal (n=6) |
R HTR (n=8) |
|---|---|---|---|---|---|---|
| ARMS2 rs10490924 | G/T | T is Risk | 9 (39%) | 14 (67%) | 2 (33%) | 4 (50%) |
| ARMS2 rs10664316 | delAT | - is Protective | 5 (22%) | 10 (48%) | 0 (0%) | 1 (13%) |
| CFH rs1061170 | T/C | C is Risk | 0 (0%) | 0 (0%) | 0 (0%) | 4 (50%) |
| CFH rs12144939 | G/T | T is Protective | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| CFH rs16840422 | C/T | T is Protective | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| CFH rs2284664 | C/T | T is Protective | 2 (9%) | 1 (5%) | 2 (33%) | 6 (75%) |
| CFH rs800292 | G/A | A is Protective | 2 (9%) | 1 (5%) | 2 (33%) | 6 (75%) |
| CFHR2 rs12066959 | C/T | C is Risk | 1 (4%) | 1 (5%) | 3 (50%) | 6 (75%) |
| HTRA rs11200638 | G/A | A is Risk | 0 (0%) | 1 (5%) | 1 (17%) | 0 (0%) |
| HTRA rs1049331 | C/T | T is Risk | 0 (0%) | 1 (5%) | 1 (17%) | 0 (0%) |
| HTRA rs2293870 | G/T/C | T/C is Risk | 1 (4%) | 1 (5%) | 3 (50%) | 1 (13%) |
| HTRA rs2672598 | T/C | C is Risk | 3 (13%) | 2 (10%) | 4 (67%) | 4 (50%) |
| ROBO1 rs1387665 | C/T | T is Risk | 0 (0%) | 1 (5%) | 1 (17%) | 2 (25%) |
| ROBO1 rs4513416 | G/A | A is Protective | 1 (4%) | 0 (0%) | 2 (33%) | 2 (25%) |
| ROBO1 rs7622444 | C/T | C is Risk | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| ROBO1 rs9809833 | T/C | C is Risk | 3 (13%) | 1 (5%) | 0 (0%) | 1 (13%) |
| RORA rs12900948 | A/G | G is Protective | 1 (4%) | 1 (5%) | 0 (0%) | 1 (13%) |
| RORA rs730754 | A/G | G is Protective | 1 (4%) | 1 (5%) | 1 (17%) | 3 (38%) |
| RORA rs8034864 | C/A | A is Risk | 3 (13%) | 2 (10%) | 2 (33%) | 4 (50%) |