Table 7:
Allele Frequencies of American Indians and Ranchers in Normal Subjects.
| SNP | Retinal Disease Effect |
Alleles | American Indian |
Rancher | Odds Ratio (95% CI) |
p-value |
|---|---|---|---|---|---|---|
| ARMS2 rs10490924 | T is Risk | G/T | 1.00 | 1.000 | - | - |
| ARMS2 rs10664316 | - is Protective | -AT | .800 | .800 | 1.000 (.086–11.588) | 1.000 |
| CFH rs1061170 | C is Risk | T/C | .200 | .400 | .375 (.046 – 3.056) | .360 |
| CFH rs12144939 | T is Protective | G/T | .150 | .600 | .118 (.013–1.03) | .053 |
| CFH rs16840422 | T is Protective | C/T | .095 | .400 | .158 (.016–1.586) | .117 |
| CFH rs2284664 | T is Protective | C/T | .524 | 1.000 | - | - |
| CFH rs800292 | A is Protective | G/A | .524 | .600 | .733 (.101–5.330) | .759 |
| CFHR2 rs12066959 | G is Risk | A/G | .350 | 1.000 | - | - |
| HTRA rs11200638 | A is Risk | G/A | .400 | .474 | 1.350 (.182–10.006) | .769 |
| HTRA1 rs1049331 | T is Risk | C/T | .524 | .400 | 1.650 (.227–11.993) | .621 |
| HTRA1 rs2293870 | T/C is Risk | G/T/C | .524 | .600 | .733 (.101–5.330) | .759 |
| HTRA1 rs2672598 | C is Risk | T/C | .600 | .600 | 1.000(.135–7.392) | 1.000 |
| ROBO1 rs1387665 | T is Risk | C/T | .400 | .300 | .643 (.085–4.889) | .669 |
| ROBO1 rs4513416 | A is Protective | G/A | .450 | .400 | 1.227 (.167–9.017) | .840 |
| ROBO1 rs7622444 | C is Risk | T/C | .158 | .000 | - | - |
| ROBO1 rs9809833 | C is Risk | T/C | .200 | .200 | 1.000 (.086–11.588) | 1.000 |
| RORA rs12900948 | G is Protective | A/G | .600 | .400 | 2.250 (.304–16.632) | .427 |
| RORA rs730754 | G is Protective | A/G | .600 | .400 | 2.250 (.304–16.632) | .427 |
| RORA rs8034864 | A is Risk | C/A | .600 | .800 | .375(.035–3.999) | .417 |