Table 4:

Differentiation of Various Groups with T1, T2, and ADC and Their Combinations

Note.—One thousand bootstrap resamples with replacement from the data and leave-one-out cross validation were performed. Numbers in parentheses are bootstrap 95% confidence intervals. ADC = apparent diffusion coefficient, AUC = area under the receiver operating characteristic curve, NTZ = normal transition zone, PI-RADS = Prostate Imaging Reporting and Data System. Clinically significant cancers were those with a Gleason score of 7 or greater; clinically insignificant lesions were low-grade/Gleason 6 cancers, prostatitis, and lesions with a diagnosis of benign prostatic tissue at biopsy.

*Multivariable regression models were not tested for PI-RADS version 2 category 3 lesions because of the small numbers of category 3 cancers.