Table 3.
Rating scores and 25(OH)D levels in children that have CTDs before and after vitamin D3 supplementation
| Variable | Baseline | After 3 months | t (Z) | p |
|---|---|---|---|---|
| YGTSS total scores | 41±11 | 26±13a | 9.68 | <0.001 |
| Total tics scores | 23±5 | 13±7a | 10.15 | <0.001 |
| Motor tics | 16 (13–18) | 10 (7–12)a | (−5.0) | <0.001 |
| Phonic tics | 8 (5–10) | 5 (2–7)a | (−4.44) | <0.001 |
| Impairment | 20 (10–20) | 10 (10–20)a | (−3.83) | <0.001 |
| CGI-SI scores | 4 (4–5) | 3 (2–4)a | (−3.79) | <0.001 |
| CGI-SI (%) | (−3.38) | 0.001 | ||
| 1–2 scores | 1 (3%) | 9 (25%)a | ||
| 3–4 scores | 23 (64%) | 24 (67%) | ||
| 5–6 scores | 12 (33%) | 3 (8%)a | ||
| 25(OH)D(ng/mL) | 21(15–23) | 51(43–58)a | (−5.23) | <0.001 |
Note: Data are means ± SD or medians (P25–P75), percentage of children. Paired t-tests, Wilcoxon tests, and Mann–Whitney tests were used to compare before and after therapy in children with CTDs. aSignificantly different from the baseline (p<0.05).
Abbreviations: 25(OH)D, 25-hydroxyvitamin D; CTDs, chronic tic disorders; YGTSS, Yale Global Tic Severity Scale.