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. 2019 Aug 30;14(8):e0221806. doi: 10.1371/journal.pone.0221806

Table 4. Cox-regression survival analysis of patients hospitalized with Chronic liver disease (CLD) in relation to selected clinical findings as predictors.

Factors CHR[95% CI ] P-value AHR[95% CI ] P-value
khat chewing history
Yes 0.466[0.214–1.015] 0.055 0.299 [0.043–2.083] 0.223
No 1 1
Cigarette smoking history
Yes 1.985[0.842–4.677] 0.117 2.101[0.158–27.939] 0.574
No 1 1
Hepatic encephalopathy 0.011
Yes 2.708 [1.252–5.859] 11.361[2.391–53.987] 0.002ǂ
No 1 1
HBsAg+ 0.570[0.265–1.230] 0.152 1.395[0.1502–12.959] 0.770
Unidentified risk factor/etiology 2.113[1.012–4.437] 0.046 5.803[1.380–24.405] 0.016ǂ
Yes 0.577 [0.078 4.261] 0.59
No 1
MAP, mmHg 0.973 [0.940–1.007] 0.117 0.962[0.888–1.042] 0.346
WBC, (109/L) 1.036 [0.986–1.089] 0.161 1.056[0.941–1.186] 0.351
Hgb, g/dl 1.010 [0.897–1.137] 0.868
MCV, fl 1.005 [1.00–1.007] <0.001 1.005[0.999–1.011] 0.095
Total bilirubin, mg/dl 1.084[1.034–1.138] 0.001 1.188[1.0719–1.316] 0.001ǂ
ALT, u/l, 1.004 [0.998–1.010] 0.240 0.992 [0.981–1.004] 0.194
Scr, mg/dl 1.233[1.016–1.495] 0.034 0.686[0.459–1.025] 0.066
Nodular liver surface 0.475[0.178–1.266] 0.136 3.699[0.724–18.895] 0.116
  Splenomegaly 0 .532[0.236–1.2] 0.128 2.236[0.540–9.267] 0.267
Heterogeneous echotexture 5.906[2.484–14.044] 0.000 2.645[0.403–17.358] 0.311
In-hospital acute
  Complication of CLD
Yes 1.607[0.752–3.432] 0.221 1.886 [0.413–8.613] 0.413
No 1

ALT- Alanine aminotransferase; CLD-Chronic Liver Disease; HBsAg- Hepatitis B Virus Surface Antigen; MAP- Mean Arterial Pressure, MCV-Mean Corpuscular Volume; WBC-White Blood Cell Count; Scr-Serum Creatinine

ǂ Statistically significant