Table 4. Pathways of target genes from the 8 miRNAs differentially expressed between tumor and healthy serum of colorectal cancer patients.
| KEGG pathway | P value1 | Genes2 | miRNAs3 |
|---|---|---|---|
| Prion diseases | <0.0001 | 1 | 1 |
| ECM-receptor interaction | <0.0001 | 10 | 3 |
| Mucin type O-Glycan biosynthesis | <0.0001 | 4 | 3 |
| Signaling pathways regulating pluripotency of stem cells | 0.0004 | 17 | 3 |
| Thyroid hormone signaling pathway | 0.0005 | 16 | 4 |
| Biotin metabolism | 0.0013 | 1 | 1 |
| Amoebiasis | 0.0070 | 11 | 2 |
| Glycosaminoglycan biosynthesis | 0.0279 | 3 | 2 |
1Only pathways with P values lower than 0.05 were considered as significant
2Number of genes affected in the pathway by the regulated miRNAs
3Number of miRNAs differentially expressed that have a target gene in the pathway